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Villani Simona

Professore associato
Martedì 14:00-15:30
svillani (at) unipv.it
Dipartimento di Scienze Sanitarie Applicate e Psicocomportamentali

Elenco corsi

Biostatistica e bioinformatica

+ Altri anni accademici

Biostatistica e bioinformatica
Biostatistica e bioinformatica

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From December 2010 Assistant Professeor in Medical Statistics at the Faculty of Medicine of Pavia University.
2002-2010 Research Assistant in Medical Statistics at the Faculty of Medicine of Pavia University.
Head of the Unit of Population Surveys, Department of Applied Health Sciences.
1990 Graduated cum laude in Biology.
1995 specialized cum laude in Medical Statistics at the University of Pavia.
2000 PhD in Biostatistics at the University of Milan.
2000-2001 Research Assistant adjunct in Medical Statistics at University of Pavia.
Teaching Medical Statistics, Epidemiology, Statistics for Experimental Research, Biometry, Anthropometry, Health Statistics, Health Management in the following courses:
-undergraduate courses for Health Professionals,
-specialization school in Medical Statistics,
-Master in Biostatistics and Epidemiology, and Health Management of the University of Pavia and Messina.
Fellow of international and national Statistics and Epidemiology Societies (International Biometrics Society, Italian Society for Medical Statistics or SISMEC), of international and national study groups on asthma (European Community Respiratory Health Survey and Italian Study of Asthma in Young Adults) and of Local Agenda 21
National coordinator of the working study group on "Observational study" for the SISMEC.
Author of more than 150 publications.

Temi di ricerca

Epidemiological Investigation
  • Epidemiology of asthma in Europe (European Community Respiratory Health Survey) and in Italy (Italian Study of Asthma in Young Adults [ISAYA]).
  • Environmental epidemiology (Gene-Environmental Interaction on Respiratory Diseases [GEIRD]) and Agenda21 in the Province and city of Pavia.
  • Experimental epidemiology on biotechnology and veterinary field.
  • Epidemiology of Alzheimer in homogenous population in the province of Milan.
  • Epidemiology of burnout in physician and nurses for the Hospital of the province of Pavia.
  • Psychiatric epidemiology in adolescent; borderline personality disorders
  • Cancer Mortality and morbidity in the Province of Lodi.

Progetti di ricerca

European Community Respiratory Health Survey

Gene-Environment Interaction on Respiratory Diseases

InVe.Ce.Ab. Study on prevalence, incidence and risk factor for Alzheimer and senile dementia

Study on prevalence and determinant of burnout in physician and nurses



Journals articles
-           Verlato G, Bortolami O, Accordino S, Olivieri M, Cappa V, Bugiani M, Corsico A, Pirina P, Villani, S; de Marco R. Asthma in childhood reduces smoking initiation in subsequent teenage among males. Accepted by Journal of Adolescent Health on July 2010. [IF09= 3.325]
-           Faustini M, Bucco M, Chlapanidas T, Marazzi M, Tosca M, Gaetani P, Klinger M, Villani S, Ferretti VV, Vigo D, Torre ML. Non expanded mesenchymal stem cells for regenerative medicine: yield in stromal vascular fraction from adipose tissues. Accepted on Tissue engineering Part C, Methods, May 2010. [IF09= 4.585]
-           Henneberger PK, Mirabelli MC, Kogevinas M, Antó JM, Plana E, Dahlman-Höglund A, Jarvis D, Kromhout H, Lillienberg L, Norbäck D, Olivieri M, Radon K, Torén K, Urrutia I, VILLANI S, Zock J. The occupational contribution to severe exacerbation of asthma. Accepted by European Respiratory Journal February 2010. [IF09= 5.527]
-           Olivieri M, Mirabelli MC, Plana E, Radon K, Antó JM, Bakke P, Benke G, D'Errico A, Henneberger P, Kromhout H, Norbäck D, Torén K, van Sprundel M, VILLANI S, Wieslander G, Zock JP, Kogevinas M. Healthy hire effect on job selection and inhalation exposure among young adults with asthma. Accepted by European Respiratory Journal February 2010. [IF09= 5.527]
-           Svanes C, Sunyer J, Plana E, Dharmage S, Heinrich J, Jarvis D, de Marco R, Norbäck Dan, Raherison C, VILLANI S, Wjst M, Svanes K, Antó JM. Early life origins of chronic obstructive pulmonary disease. Thorax 2010, 65: 14-20. doi: 10.1136/thx.2008.112136. Epub 2009 - PMID: 19729360. [IF09= 7.041]
-           Verlato G, Melotti R, Olivieri M, Corsico A, Bugiani M, Accordini S, VILLANI S, Migliore E, Marinoni A, Pirina P, Carrozzi L, Bortolami O, Rava M, de Marco1 R, for the ISAYA study group. Asthmatics and ex-smokers respond early, heavy smokers respond late to mailed surveys in Italy. Respiratory Medicine 2010, 104(2):172-9. Epub 2009 Oct 25. PMID: 19857946 [IF09= 2.331]
-           Faustini M, Bucco M, Galeati G, Spinaci M, VILLANI S, Chlapanidas T, Ghidoni I, Vigo D, Torre ML. Boar sperm encapsulation reduces in vitro polyspermy. In press on Reproduction in Domestic Animals, doi: 10.1111/j.1439-0531.2008.01213.x. (Accepted on April 2008, published on-line 22 december 2008) [IF09= 1.606]
-           The GEIRD Study Group. The Genes Environment Interactions in Respiratory Diseases (GEIRD) Project. International Archives of Allergy and Immunology 2010, 152(3):255-63. Epub 2010 Feb 11. [IF09=2.542]
-           Zock JP, Plana E, Antó JM, Benke G, Blanc PD, Carosso A, Dahlman-Höglund A, Heinrich J, Jarvis D, Kromhout H, Lillienberg L, Mirabelli MC, Norbäck D, Olivieri M, Ponzio M, Radon K, Soon A, van Sprundel M, Sunyer J, Svanes C, Torén K, Verlato G, Villani S, Kogevinas M. Domestic use of hypochlorite bleach, atopic sensitization and respiratory symptoms in adults. Journal of Allergy and Clinical Immunology 2009, 124 (4): 731-8; e1. PMID: 19665775. [IF09=9.165]
-           Traversi D, Degan R, De Marco R, Gilli G, Pignata C, VILLANI S, Bono R. Mutagenic properties of PM2.5 urban pollution in the Northern Italy: The nitro-compounds contribution. Environment International 2009, 35(6):905-10. Epub 2009 Apr 29 - PMID: 19406477. [Epub ahead of print]. [IF09= 4.786]
-           Vigo D, Faustini M, VILLANI S, Orsini F, Bucco M, Chlapanidas T, Conte U, Ellis K, Torre ML. Semen controlled-release capsules allow a single artificial insemination in sows. Theriogenology 2009, 72(4): 439-44. Epub 2009 Jun 7. [IF09= 2.073]
-           Grisoli P, Rodolfi M, VILLANI S, Grignani E, Cottica D, Berri A, Picco AM, Dacarro C. Assessment of Airborne Microorganism Contamination in an Industrial Area characterized by an Open Composting Facility and a Wastewater Treatment Plant. Environmental Research 2009;109(2): 135-42. [IF09= 3.237]
-           Mirabelli MC, Zock JP, Bircher AJ, Jarvis D, Keidel D, Kromhout H, Norbäck D, Olivieri M, Plana E, Radon K, Schindler C, Schmid-Grendelmeier P, Torén K, VILLANI S, Kogevinas M. Metalworking exposures and current persistent skin symptoms in the ECRHS II and SAPALDIA 2 cohorts. Contact Dermatitis 2009, 60(5):256-263. [IF09= 3.635]
-           Bergamaschi R, VILLANI S, Crabbio M, Tavazzi E, Franciotta D, Ponzio M, Romani A, Verri A, Cosi V. Inverse association between multiple sclerosis and respiratory allergic diseases. Neurological Sciences 2009, 30(2):115-8. Epub 2009 Mar 4. [IF09= 1.120]
-           Mirabelli MC, Zock JP, Olivieri M, Kromhout H, Norbäck D, Radon K, Torén K, VILLANI S, van Sprundel M. Inhalation incidents and respiratory health: Results from the European Community Respiratory Health Survey. American Journal of Industrial Medicine 2009, 52(1): 17–24. [IF09=1.721]
-           Götschi T, Sunyer J, Chinn S, de Marco R, Forsberg B, Gauderman JW, Garcia-Esteban R, Heinrich J, Jacquemin B, Jarvis D, Ponzio M, VILLANI S, Künzli N. Air Pollution and Lung Function in the European Community Respiratory Health Survey. International Journal of Epidemiology 2008, Dec;37(6):1349-58. Epub 2008 Jul 1, [Epub ahead of print]. [IF08= 5.838]
-           Faustini M, Riccardi A, VILLANI S, Russo V. M. L. Torre & U. Conte & D. VigoA single insemination intervention in the sow with barium alginate-encapsulated boar semen. Veterinary Research Communications (2008) 32 (Suppl 1):S147–S149 DOI 10.1007/s11259-008-9115-1. [IF08= 0.630]
-           Traversi D, Degan R, de Marco R, Gilli G, Pignata C, Ponzio M, Rava M, Sessarego F, VILLANI S, Bono R. Mutagenic properties of PM2.5 air pollution in the Padana Plain (Italy) before and in the course of XX Winter Olympic Games of “Torino 2006”. Environment International 2008, Apr 12. [Epub ahead of print]. [IF08= 3.516]
-           Colombo O, VILLANI S, Pinelli G, Trentani C, Baldi M, Tomarchio O, Tagliabue A. To treat or not to treat: comparison of different criteria used to determine whether weight loss is to be recommended. Nutrition Journal 2008, 7:5 [doi:10.1186/1475-2891-7-5]. [IM-PubMed]
-           Svanes C, Dharmage S, Sunyer J, Zock JP, Norbäck D, Wjst M, Heinrich J, Jarvis D, de Marco R, Plana E, VILLANI S, Antó JM. Long-term reliability in reporting of childhood pets by adults interviewed twice, nine years apart. Results from the European Community Respiratory Health Survey I and II. Indoor Air 2008, 18: 84–92. [IF08= 3.151]
-           VILLANI S., Marazzi M., Bucco M., Faustini M., Klinger M., Gaetani P., Crovato F., Vigo D., Caviggioli F., Torre M.L. Statistical approach in alginate membrane formulation for cell encapsulation in a GMP-based cell factory. Acta Biomaterialia 2008, 4(4): 943-9. Epub 2008 Jan 26. [IF08=3.727]
-           Munari E, Asti A, Colombani C, Benzoni E, Faustini M, Torre ML, Riccardi A, VILLANI S, Sesso L, Conte U, Vigo D. Competence of swine oocytes matured by three-dimensional gonadotropin-free co-culture. Veterinary Research Communications 2007, 31 (Suppl 1): 181-4. [IF07=0.529]
-           Zock JP, Plana E, Jarvis D, Antó JM, Kromhout H, Kennedy SM, Künzli Nino, VILLANI S, Olivieri M, Torén K, Radon K, Sunyer J, Dahlman-Hoglund A, Norbäck D, Kogevinas M. The use of household cleaning sprays and adult asthma: an international longitudinal study. American Journal of Respiratory and Critical Care Medicine 2007, 176: 735-41. Epub ahead of print 10.1164/rccm.200612-1793OC. [IF07=9.074]
-           Kogevinas M, Zock JP, Jarvis D, Kromhout H, Lillienberg L, Plana E, Radon K, Torén K, Alliksoo A, Benke G, Blanc PD, Dahlman-Hoglund A, D'Errico A, Héry M, Kennedy S, Kunzli N, Leynaert B, Mirabelli MC, Muniozguren N, Norbäck D, Olivieri M, Payo F, VILLANI S, van Sprundel M, Urrutia I, Wieslander G, Sunyer J, Antó JM. Exposure to substances in the workplace and new-onset asthma: an international prospective population-based study (ECRHS-II). Lancet 2007, 307: 336-341. [IF07=28.638]
-           Mirabelli MC, Zock JP, Plana E, Benke G, Kromhout H, Norbäck D, Olivieri M, Radon K, VILLANI S, Kogevinas M. Employment status and use of respiratory protection among metalworkers, solderers and welders. Occupational and Environmental Medicine 2007, 64(8): 548-52. Epub 2007 Mar 26. [IF07=2.817]
-           Mirabelli MC, Zock JP, Plana E, Antó JM, Benke G, Blanc P, Dahlman-Höglund A, Jarvis DL, Kromhout H, Lillienberg L, Norbäck D, Olivieri M, Radon K, Sunyer J, Torén K, van Sprundel M, VILLANI S, Kogevinas M. Occupational risk factors for asthma among nurses and related healthcare professionals in an international study. Occupational and Environmental Medicine 2007, 64(7): 474-9. Epub 2007 Mar 1. [IF07=2.817]
-           Jarvis D, Zock JP, Heinrich J, Svanes C, Verlato G, Olivieri M, VILLANI S, Ponzio M, Leynaert B, Sunyer J, Dahlman-Hoglund A, Chinn S, Luczynska C, Norbäck D, Burney P. Cat and dust mite allergen levels, specific IgG and IgG4, and respiratory symptoms in adults. Journal of Allergy and Clinical Immunology 2007, 119(3): 697-704. Epub 2007 Jan 30. [IF07=8.115]
-           Harrop J, Chinn S, Verlato G, Olivieri M, Norback D, Wjst M, Janson C, Zock JP, Leynaert B, Gislason D, Ponzio M, VILLANI S, Carosso A, Svanes C, Heinrich J, Jarvis D. Eczema, atopy and allergen exposure in adults: a population-based study. Clinical and Experimental Allergy 2007, 37(4): 526-35. [IF07=3.729]
-           Corsico A, Cazzoletti L, de Marco R, Janson C, Jarvis D, Zoia MC, Bugiani M, Accordini S, VILLANI S, Marinoni A, Gislason D, Gulsvik A, Pin I, Vermeire P, Cerveri I. Factors affecting adherence to asthma treatment in an international cohort of young and middle-aged adults. Respiratory Medicine 2007, 101(6): 1363-7. Epub 2006 Dec 26. [IF07=2.235]
-           Sunyer J, Jarvis D, Gotschi T, Garcia-Esteban R, Jacquemin B, Aguilera I, Ackerman U, de Marco R, Forsberg B, Gislason T, Heinrich J, Norbäck D, VILLANI S and Kunzli N. Chronic bronchitis and urban air pollution in an international study. Occupational and Environmental Medicine 2006, 63(12): 836-43. Epub 2006 Jul 17. [IF06=2.255
-           Torre ML, Munari E, Albani E, Levi-Setti PE, VILLANI S, Faustini M, Conte U, and Vigo D. In vitro maturation of human oocytes in a follicle-mimicking three-dimensional coculture. Fertility and Sterility 2006, 86(3):572-6. Epub 2006 Jul 3. [IF06=3.277]
-           Zock JP, Heinrich J, Jarvis D, Verlato G, Norbäck D, Plana E, Sunyer J, Chinn S, Olivieri M, Soon A, VILLANI S, Ponzio M, Dahlman-Hoglund A, Svanes C, Luczynska C. Distribution and determinants of house dust mite allergens in Europe: The European Community Respiratory Health Survey II. Journal of Allergy and Clinical Immunology 2006, 118: 682-690. [IF06= 8.829]
-           Heinrich J, Bero Bedada G, Zock JP, Chinn S, Norbäck D, Olivieri M, Svanes C, Ponzio M, Verlato G, VILLANI S, Jarvis D, Luczynska C for the Indoor Factor Working Group of the ECRHS Study Group. Cat allergen levels, its determinants and relationship to specific IgE to cat across European centers. Journal of Allergy and Clinical Immunology 2006, 118: 674-681. [IF06= 8.829]
-           Sunyer J, Zock JP, Kromhout H, Garcia-Esteban R, Radon K, Jarvis D, Toren K, Künzli N, Norbäck D, d’Errico A, Urrutia Isabel, Payo F, Olivieri M, VILLANI S, Van Sprundel M, Antó JM, Kogevinas M for the occupational group of the ECRHS study. Lung function decline, chronic bronchitis and occupational exposures in young adults. American Journal of Respiratory and Critical Care Medicine 2005, 172(9):1139-1145. [IF05=8.689]
-           Benzoni E, Torre ML, Faustini M, Stacchezzini S, Cremonesi F, Conte U, VILLANI S, Russo V, Ricevuti G and Vigo D. Transient transfection of porcine granulosa cells after 3D culture in barium alginate capsules. International Journal of Immunopathology and Pharmacology 2005, 18(4), 677-681. [IF05=3.418].
-           Wist M, Dharmage S, André E, Norback D, Raherison S, VILLANI S, Manfreda J, Sunyer J, Jarvis D, Burney P, Svanes C. Latitude, birth date, and allergy. PLoS Medicine 2005, 2(10): 979-986. [IF05=8.389]
-           Götschi T, Hazenkamp-von Arx ME, Heinrich J, Bono R, Burney P, Forsberg B, Jarvis D, Maldonado JA, Norbäck D, Stern WB, Sunyer J, Torén, Verlato G, VILLANI S, Künzli N. Elemental composition and reflectance of ambient fine particles at 21 European locations. Atmospheric Environment 2005, 39: 5947-5958. [IF05=2.724]
-           Vigo D, VILLANI S, Faustini M, Accorsi PA, Galeati G, Munari E, Russo V, Asti A, Conte U, Torre ML. Follicle-like model by granulosa cell encapsulation in a barium alginate/protamine membrane. Tissue Engineering 2005, 11(5-6): 709-714. [IF05=2.887]
-           Toselli AL, VILLANI S, Ferro AM, Verri A, Cucurullo L, Marinoni A (2005). Eating Attitudes and their correlates in high school adolescents of Northern Italy. Epidemiologia e Psichiatria Sociale 2005, 14(2): 91-99. [IM-PubMed e IF dal 2008=2.9]
-           Dacarro. C, Grisoli P, Del Frate G, VILLANI S, Grignani E, Cottica D. Micro-organisms and dust exposure in an Italian grain mill. Journal of Applied Microbiology 2005, 98(1): 163-171. [IF05=2.127]
-           Vigo D, Torre ML, Faustini M, Spinaci M, Munari E, Russo V, Norberti R, VILLANI S, Asti A, Bini PP and Conte U. Barium alginate capsules for 3D immobilisation of living cells: morphology, membrane properties and permeability. Journal of Drug Delivery Science and Technology 2004, 14(3): 167-172. [IF dal 2005]
-           Hazenkamp-von Arx ME, Götschi T, Ackermann-Liebrich U, Bono R, Burney P, Cyrys J, Jarvis D, Lillienberg L, Luczynska C, Maldonado JA, Jaén A, de Marco R, Mi Y, Modig L, Bayer-Oglesby L, Payo F, Soon A, Sunyer J, VILLANI S, Weyler J, Künzli N. PM2.5 and NO2 Assessment in 21 European Study Centres of ECRHS II. Annual Means and Seasonal Differences. Atmospheric Environment 2004, 38: 1943-1953. [IF04=2.562]
-           Zanolin ME, Pattaro C, Corsico A, Bugiani M, Carrozzi L, Casali L, Dallari R, Ferrari M, Marinoni A, Migliore E, Olivieri M, Pirina P, Verlato G, VILLANI S and de Marco R for the ISAYA Study Group. The role of climate on the geographic variability of asthma, allergic rhinitis and respiratory symptoms: results from the Italian Study of Asthma in Young Adults (ISAYA). Allergy 2004, 59: 306-314. [IF04=3.496]
-           Verlato G, Corsico A, VILLANI S, Cerveri I, Migliore E, Accordini S, Carolei A, Piccioni P, Bugiani M, Lo Cascio V, Marinoni A, Poli A, de Marco R. Is the prevalence of adult asthma and allergic rhinitis still increasing? Results of an Italian study. Journal of Allergy and Clinical Immunology 2003, 111(6): 1232-1238. [IF03=6.831]
-           de Marco R, Poli A, Ferrari M, Accordini S, Giammanco G, Bugiani M, VILLANI S, Ponzio M, Bono R, Carrozzi L, Cavallini R, Cazzoletti L, Dallari R, Ginesu F, Lauriola P, Mandrioli P, Perfetti L, Pignato S, Pirina P, Struzzo P for the ISAYA study group. The impact of climate and traffic-related NO2 on prevalence of asthma and allergic rhinitis in Italy. Clinical and Experimental Allergy 2002, 32: 1405-1412. [IF02=3.721]
-           Vigo D, Faustini M, Torre ML, Pecile A, VILLANI S, Asti A, Norberti R, Maggi L, Conte U, Cremonesi F, Stacchezzini S, Maffeo G. Boar semen controlled-delivery system: morphological investigation and in vitro investigation test. Reproduction Fertility and Development 2002, 14: 307-314. [IF02=0.959]
-           Grassi M, VILLANI S, Marinoni A. Classification methods for the identification of case in epidemiological diagnosis of asthma. European Journal of Epidemiology 2001; 17(1): 19-29. [IF01=0.674]
-           Marinoni A, Degrate A, VILLANI S, Gerzeli S & Working Group. Psychological distress and its correlates in secondary school students in Pavia, Italy. European Journal of Epidemiology 1997; 13(7): 779-786. [IF 0.762]
-           VILLANI S, Grassi M, Marinoni A. Lo stato di salute negli adolescenti: quali relazioni con l’immagine della famiglia? Epidemiologia e Psichiatria Sociale 1997; 6(1): 59-68. [IM-PubMed, e IF dal 2008=2.9]
Chapters of books
-           VILLANI S. La qualità dell’aria in ambiente confinati, in AA.VV. ‘Segnali ambientali. Rapporto sullo Stato dell’Ambiente in Lombardia 2008-2009’- ARPA della Lombardia. Milano, 2009, pp. 42.
-           Marinoni A, VILLANI S, Morandi A, Frigerio F, Verri A. Uso dei mezzi di trasporto in ambiente urbano. Indagine epidemiologica trasversale su un campione di popolazione pavese. In: Morandi A, Verri A, VILLANI S. Salute, qualità ambientale e stili di vita. Pavia: La Goliardica Pavese 2004
-           Verlato G, Villani S. La prevalenza di asma ed atopia nella popolazione adulta. In: de Marco Roberto, Bugiani Massimiliano, Cerveri Isa, Lo Cascio Vincenzo, Marinoni Alessandra. L'Epidemiologia dell'asma in Italia. Bologna: Edi-Aipo Scientifica 2001. ISBN: 88-87398-26-7.
-           Gerzeli S, Villani S, Degrate A, Marinoni A (1996). Comportamenti, abitudini di vita e relazioni familiari negli adolescenti. In: Bolzan F, Fabbri L, Perissinotto E. Salute e Famiglia. Metodi di produzione e analisi statistica di dati. Padova: Edizioni CLEUP 1996: 163-170.
-           Degrate A, Villani S, Gerzeli S, Marinoni A. Famiglia e umore depresso negli adolescenti. In: Bolzan F, Fabbri L, Perissinotto E. Salute e Famiglia. Metodi di produzione e analisi statistica di dati. Padova: Edizioni CLEUP 1996: 157-161
-           Villani S, Gerzeli S, Degrate A, Grassi M, Marinoni A. Stato di salute degli adolescenti e immagine della famiglia: evidenze da uno studio epidemiologico. In: Bolzan F, Fabbri L, Perissinotto E. Salute e Famiglia. Metodi di produzione e analisi statistica di dati. Padova: Edizioni CLEUP 1996: 171-177.

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